Evidence recordApplied to skin
Snail Secretion Filtrate
Answer
One small placebo-controlled trial found fewer inflammatory lesions with a three-ingredient serum containing snail secretion filtrate.
Check the formulaEvidence grade
Limited
The record is early, small, indirect, mixed or tightly tied to one formulation.
Where it stops
The serum also contained calendula and licorice, so the effect cannot be attributed to snail secretion filtrate alone. Non-inflammatory lesions and measured skin biophysics did not differ; a 2024 review found most wider claims rest on preclinical or small clinical studies.
Sources
Sources · 2
Source 1
J Cosmet Dermatol, 2022- Design
- Randomized double-blind placebo-controlled trial
- Participants
- 66
- Duration
- 12 weeks
- Measured outcome
- inflammatory acne lesions, non-inflammatory acne lesions, sebum, corneometry, transepidermal water loss, erythema
- Studied formulation
- snail secretion filtrate, calendula and licorice serum, placebo serum
Finding
Twelve-week randomized double-blind placebo-controlled trial in 66 people with mild-to-moderate mask-related acne: the three-ingredient serum reduced inflammatory lesions more than placebo, while non-inflammatory lesions and measured skin biophysics did not significantly differ. Snail secretion filtrate was not tested alone.
Source 2
J Cosmet Dermatol, 2024- Design
- Literature review
- Measured outcome
- clinical evidence limitations, allergy investigation, ethical extraction
- Studied formulation
- snail mucin and snail extract preparations
Finding
Literature review of medical and cosmetic uses: most studies were preclinical or small clinical studies, and larger clinical trials are needed to support claimed benefits and clarify safety and ethical-extraction questions.