Ingredient guide
sh-Octapeptide-1
INCI name · sh-octapeptide-1
In short
sh‑Octapeptide‑1 is a mimic of keratinocyte growth factor, used to support the skin’s barrier and surface renewal. It helps skin feel stronger and look more even over time.
Works forFrom reviewed ingredient data
Firmness · Barrier
Best used
Evening
What it is
Synthetic octapeptide that mimics the receptor-binding region of keratinocyte growth factor (KGF/FGF-7); activates FGFR2b on keratinocytes and sebocytes; KGF signalling supports barrier function, accelerates wound healing, and stimulates epidermal renewal; as a small stable synthetic analogue it overcomes the formulation and regulatory challenges of using intact recombinant KGF protein; used in advanced anti-ageing and barrier recovery serums.
Evidence receipt
No linked study yet
No verified study is linked to this exact ingredient and route. The guidance below describes conventional use; it is not evidence of efficacy.
When to use it
Evenings suit it best.
Where it sits
Serums sit after toner and before moisturiser. Thinnest to thickest, water before oil.
- Cleanse
- Tone
- sh-Octapeptide-1
- Moisturise
- SPF
Also found as
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Check an ingredient listCommon questions
What does sh‑Octapeptide‑1 do for skin?
It encourages barrier comfort and promotes smoother, healthier‑looking skin.
Which skin types benefit from sh‑Octapeptide‑1?
Most skin types can use it, especially those seeking barrier support and improved texture.
How is sh‑Octapeptide‑1 typically used?
It appears in concentrated serums and is often paired with hydrating or restorative ingredients.
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Personal guidance, not medical advice.