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Ingredient guide
nicotinoyl dipeptide-22
In short
Nicotinoyl Dipeptide‑22 is a newer biomimetic peptide designed to mimic retinol‑like signalling with a gentler feel. Early data points to support for skin smoothness and brightness.
Reviewed against published evidence · editorially independent · no brand pays for placement
Works for
Firmness · Texture · Tone
Skin type
Dry · Sensitive
Best used
Evening
What it is
Biomimetic peptide with a nicotinoyl moiety designed to activate retinol-like signalling pathways without retinoid irritation. Early data suggests collagen-supportive and brightening activity. A newer option for retinol-sensitive routines.
Also found as
Related
Common questions
It aims to encourage smoother texture and a more even look, inspired by retinol pathways.
It was designed with gentleness in mind, making it an option for those who avoid traditional retinoids.
Research is emerging, with promising but still early-stage data.
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Personal guidance only · For clinical concerns, see a dermatologist.