Ingredient guide
Isopeptide-4
INCI name · isopeptide-4
In short
Isopeptide-4 is a synthetic peptide that mimics natural cross‑linking bonds formed in the outer skin layers. It may help improve surface texture by supporting the skin’s structural envelope.
What it is
Synthetic peptide that mimics transglutaminase cross-linking bonds. May promote cornified envelope formation and improve skin surface texture.
Evidence receipt
No linked study yet
No verified study is linked to this exact ingredient and route. The guidance below describes conventional use; it is not evidence of efficacy.
Where it sits
Serums sit after toner and before moisturiser. Thinnest to thickest, water before oil.
- Cleanse
- Tone
- Isopeptide-4
- Moisturise
- SPF
Also found as
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Check an ingredient listCommon questions
What does Isopeptide-4 do for skin?
It aims to support the formation of a smoother, more uniform surface layer, improving overall texture.
Who might benefit from Isopeptide-4?
Anyone looking to refine visible texture or support skin resilience may find it useful.
How is Isopeptide-4 used in skincare?
It is usually blended into serums or creams targeting smoother-looking skin.
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Personal guidance, not medical advice.