Ingredient guide
Hydroxyphenyl Propamidobenzoic Acid (Sebokalyne)
INCI name · hydroxyphenyl propamidobenzoic acid
In short
Hydroxyphenyl Propamidobenzoic Acid (Sebokalyne) is a sebum‑modulating ingredient that helps reduce the look of enlarged pores and refine texture. It works by influencing pathways involved in oil production and surface buildup.
What it is
Commercially Sebokalyne (Sederma); modulates sebum secretion by reducing 5-alpha-reductase type I/II activity and suppressing lipogenic gene expression (SREBP-1, FAS) in sebocytes; visibly reduces pore size over 4-6 weeks of use; mild keratolytic secondary effect reduces follicular cast formation; often combined with niacinamide, zinc PCA or salicylic acid for synergistic sebum control in oily-skin and pore-minimising formulations.
Evidence receipt
No linked study yet
No verified study is linked to this exact ingredient and route. The guidance below describes conventional use; it is not evidence of efficacy.
When to use it
Mornings suit it best.
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What does Hydroxyphenyl Propamidobenzoic Acid do for skin?
It helps reduce the appearance of enlarged pores by moderating oil output and softening excess buildup in follicles. This leads to a smoother-looking texture.
Who is this ingredient best for?
It suits skin that looks oily or shows noticeable pores, especially in the T‑zone. Its gentle approach makes it a good option for daily texture refinement.
How is it used in skincare?
It appears in serums or creams designed for pore‑minimising routines, often paired with niacinamide or salicylic acid. Availability is still relatively limited.
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Personal guidance, not medical advice.