Ingredient guide
PDRN (Sodium DNA)
INCI name · sodium dna
In short
Sodium DNA is a marine‑derived polynucleotide used for deep hydration and improved skin suppleness. It helps bind moisture and can support a plumper, more elastic look.
What it is
DNA fragments, classically salmon-derived, studied for skin recovery. Most published human evidence comes from in-clinic injections, not creams; the first small topical studies appeared in late 2025 and are directional rather than conclusive. Whether enough reaches living skin layers from a serum is the open question.
Evidence receipt
No linked study yet
No verified study is linked to this exact ingredient and route. The guidance below describes conventional use; it is not evidence of efficacy.
Where it sits
Serums sit after toner and before moisturiser. Thinnest to thickest, water before oil.
- Cleanse
- Tone
- PDRN
- Moisturise
- SPF
Also found as
Related
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Browse product comparisonsWhere to find it
Examples, not a ranking. A product lookup can confirm identity and background; a verdict still needs the full ingredient list.
medicube PDRN Pink Peptide Serum
PDRN-peptide serum for glow and resilience; keep expectations subtle and steady.
Product comparisonSee the verdict and closest alternatives.Open comparisonProduct discovery is not efficacy proof. These examples are not ranked by commission.
Common questions
What does sodium DNA do for skin?
It helps draw and hold water, leaving skin feeling more cushioned and refreshed.
Who can use sodium DNA?
Dry or sensitive skin often benefits from its moisture‑binding, comfort‑boosting qualities.
How is sodium DNA used?
It appears in hydrating essences, serums, and creams aimed at improving surface elasticity.
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Personal guidance, not medical advice.