Ingredient guide
PDRN (Sodium DNA)
sodium dna
In short
Sodium DNA is a marine‑derived polynucleotide used for deep hydration and improved skin suppleness. It helps bind moisture and can support a plumper, more elastic look.
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What it is
DNA fragments, classically salmon-derived, studied for skin recovery. Most published human evidence comes from in-clinic injections, not creams; the first small topical studies appeared in late 2025 and are directional rather than conclusive. Whether enough reaches living skin layers from a serum is the open question.
Where it sits
Serums sit after toner and before moisturiser. Thinnest to thickest, water before oil.
- Cleanse
- Tone
- PDRN
- Moisturise
- SPF
Also found as
Related
Where to find it
Options across the range, not a ranking. Run one through Lens and MIRU will tell you if it fits you.
The mainline pick
medicube PDRN Pink Peptide Serum
PDRN-peptide serum for glow and resilience; keep expectations subtle and steady.
Fit comes first: the Lens checks each product against your skin before any retailer link. We may earn a commission, at no cost to you. Picks are editorial, never paid.
Common questions
What does sodium DNA do for skin?
It helps draw and hold water, leaving skin feeling more cushioned and refreshed.
Who can use sodium DNA?
Dry or sensitive skin often benefits from its moisture‑binding, comfort‑boosting qualities.
How is sodium DNA used?
It appears in hydrating essences, serums, and creams aimed at improving surface elasticity.
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Personal guidance, not medical advice.