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Ingredient guide
sh-decapeptide-4
In short
sh‑Decapeptide‑4 is inspired by basic fibroblast growth factor and is used to support firmness and refined texture. Its small size allows stable formulation and targeted signalling.
Reviewed against published evidence · editorially independent · no brand pays for placement
Works for
Firmness · Texture
Best used
Evening
What it is
Synthetic peptide analogue based on the FGFR1-binding domain of basic fibroblast growth factor (bFGF/FGF-2); bFGF is one of the key drivers of fibroblast proliferation and collagen synthesis in the dermis; the small synthetic peptide format enables stable formulation at low pH (unlike the glycoprotein) and avoids the theoretical mitogenic safety concerns associated with full-length growth factors applied to intact skin; typically used at trace concentrations (1–100 ppb) in multi-peptide growth factor serums.
Also found as
Related
Common questions
It supports pathways linked to a firmer, smoother skin surface.
Those looking to improve visible firmness or uneven texture may find it useful.
It’s commonly found in premium serums and can be layered with antioxidants and hydrating formulas.
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Personal guidance only · For clinical concerns, see a dermatologist.