Ingredient guide
sh-Decapeptide-4 (FGF analogue)
INCI name · sh-decapeptide-4
In short
sh‑Decapeptide‑4 is inspired by basic fibroblast growth factor and is used to support firmness and refined texture. Its small size allows stable formulation and targeted signalling.
What it is
Synthetic peptide analogue based on the FGFR1-binding domain of basic fibroblast growth factor (bFGF/FGF-2); bFGF is one of the key drivers of fibroblast proliferation and collagen synthesis in the dermis; the small synthetic peptide format enables stable formulation at low pH (unlike the glycoprotein) and avoids the theoretical mitogenic safety concerns associated with full-length growth factors applied to intact skin; typically used at trace concentrations (1–100 ppb) in multi-peptide growth factor serums.
Evidence receipt
No linked study yet
No verified study is linked to this exact ingredient and route. The guidance below describes conventional use; it is not evidence of efficacy.
When to use it
Evenings suit it best.
Where it sits
Serums sit after toner and before moisturiser. Thinnest to thickest, water before oil.
- Cleanse
- Tone
- sh-Decapeptide-4
- Moisturise
- SPF
Also found as
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Check an ingredient listCommon questions
What does sh‑Decapeptide‑4 do for skin?
It supports pathways linked to a firmer, smoother skin surface.
Who is sh‑Decapeptide‑4 suitable for?
Those looking to improve visible firmness or uneven texture may find it useful.
How is sh‑Decapeptide‑4 used?
It’s commonly found in premium serums and can be layered with antioxidants and hydrating formulas.
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Personal guidance, not medical advice.