Ingredient guide
Lactotripeptide (IPP/VPP)
INCI name · lactotripeptide
In short
Lactotripeptide is a duo of milk‑derived tripeptides known for supporting barrier comfort and skin elasticity. On skin, they’re explored for helping maintain suppleness and reducing the look of stress‑induced roughness.
Works forFrom reviewed ingredient data
Barrier · Firmness
Best used
Anytime
What it is
Mixture of Ile-Pro-Pro (IPP) and Val-Pro-Pro (VPP) tripeptides derived from casein fermentation by Lactobacillus helveticus; originally characterised as ACE (angiotensin-converting enzyme) inhibitors via oral administration; topical application studied for skin barrier support and modulation of metalloproteinase activity in UV-stressed skin; proline-containing sequences are recognised by fibroblast collagen receptors, providing a biological rationale for matrix support activity; used in anti-ageing and firming concentrates.
Evidence receipt
No linked study yet
No verified study is linked to this exact ingredient and route. The guidance below describes conventional use; it is not evidence of efficacy.
Where it sits
Serums sit after toner and before moisturiser. Thinnest to thickest, water before oil.
- Cleanse
- Tone
- Lactotripeptide
- Moisturise
- SPF
Also found as
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Check an ingredient listCommon questions
What does Lactotripeptide do for skin?
It can help the skin feel stronger and look more supple, especially under environmental stress.
Who is Lactotripeptide for?
It works for most skin types, particularly those wanting gentle barrier and elasticity support.
How is Lactotripeptide used?
You’ll usually find it in serums, moisturisers, or barrier‑focused treatments.
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Personal guidance, not medical advice.