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Ingredient guide
lactotripeptide
In short
Lactotripeptide is a duo of milk‑derived tripeptides known for supporting barrier comfort and skin elasticity. On skin, they’re explored for helping maintain suppleness and reducing the look of stress‑induced roughness.
Reviewed against published evidence · editorially independent · no brand pays for placement
Works for
Barrier · Firmness
Best used
Anytime
What it is
Mixture of Ile-Pro-Pro (IPP) and Val-Pro-Pro (VPP) tripeptides derived from casein fermentation by Lactobacillus helveticus; originally characterised as ACE (angiotensin-converting enzyme) inhibitors via oral administration; topical application studied for skin barrier support and modulation of metalloproteinase activity in UV-stressed skin; proline-containing sequences are recognised by fibroblast collagen receptors, providing a biological rationale for matrix support activity; used in anti-ageing and firming concentrates.
Also found as
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Common questions
It can help the skin feel stronger and look more supple, especially under environmental stress.
It works for most skin types, particularly those wanting gentle barrier and elasticity support.
You’ll usually find it in serums, moisturisers, or barrier‑focused treatments.
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Personal guidance only · For clinical concerns, see a dermatologist.