Ingredient guide
Lactosyl Ceramide
lactosyl ceramide
In short
Lactosyl Ceramide is a naturally occurring skin lipid that helps support barrier organisation. It contributes to keratinocyte signalling and moisture-retaining lipid structures.
Reviewed against published evidence · editorially independent · no brand pays to be featured
What it is
Glycosphingolipid found naturally in the epidermis. Participates in keratinocyte differentiation signalling and lamellar body formation for barrier function.
What the evidence says
ModerateCeramidesapplied to skin
Studied in relation to a stronger, better-hydrated skin barrier. Part of the skin’s own lipid structure.
See 2 sources
Systematic review and meta-analysis in atopic dermatitis, five studies: ceramide-containing moisturisers improved SCORAD against other moisturisers (mean difference -0.98, P=0.003). Transepidermal water loss was NOT significantly different (-3.56, P=0.17, high heterogeneity).
atopic-dermatitis severity, transepidermal water loss
Indian J Dermatol, 2023Randomised, investigator-blinded, intra-individual comparison in patients with controlled atopic dermatitis: a ceramide-precursor moisturiser on one lower leg against the untreated other leg for 4 weeks gave greater reduction in transepidermal water loss and clinical dryness and higher hydration (all P<.01).
transepidermal water loss, dryness, hydration
J Dermatolog Treat, 2013
Where it sits
It lives in the moisturiser step, sealing in the lighter layers below.
- Cleanse
- Tone
- Serum
- Lactosyl Ceramide
- SPF
Also found as
Related
N-Lignoceroyl Phytosphingosine (Ceramide C24)
Barrier · Hydration
Nervonyl Phytosphingosine (Ceramide C24:1)
Barrier · Hydration
Oleoyl Phytosphingosine
Barrier · Hydration
Palmitoyl Phytosphingosine
Barrier · Hydration
Morel Mushroom (Morchella esculenta, Polysaccharide Skin Protector)
Barrier · Hydration
Sacha inchi oil
Barrier · Hydration
Where to find it
MIRU hasn't verified a catalogue pick that leads with lactosyl ceramideyet. The Lens can check any product you're considering.
Search the Lens for lactosyl ceramideCommon questions
What does Lactosyl Ceramide do for skin?
It helps reinforce the barrier by supporting the formation of organised lipid layers that retain moisture.
Who is Lactosyl Ceramide best for?
It suits dry or sensitive skin that benefits from barrier-supportive lipids.
How is Lactosyl Ceramide used?
It’s added to creams or serums focused on replenishing and strengthening the skin’s outer layer.
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Personal guidance, not medical advice.