Ingredient guide
Centella Callus Culture Extract
INCI name · centella asiatica callus culture extract
In short
Centella callus culture extract is a lab-grown form of Centella asiatica designed to concentrate its soothing and antioxidant molecules. It offers a gentler, more controlled alternative to field-grown Centella extracts.
What it is
Plant callus culture form of Centella asiatica; biotechnology process enriches asiaticoside, madecassoside, and asiatic acid fractions while bypassing field-grown contamination risks; complements the existing centella extract and TECA entries with a cell-culture INCI distinct from whole-plant material.
Evidence receipt
LimitedCentella asiatica (cica) · applied to skin
Based on 2 sources
Open the citable recordEncouraging early evidence in relation to calmer, more comfortable skin. A long-used soothing botanical.
Studied as Centella asiatica (cica): standardised Centella extract, madecassoside.
See 2 sources
Review of topical Centella asiatica. The one controlled human result it reports for erythema is a split-face, double-blind, placebo-controlled trial of 0.05% standardised ECa 233 gel after laser resurfacing for acne scars, in which erythema subsided by day 7 against day 28 on the placebo side (Damkerngsuntorn et al. 2020). The review also describes the actives enhancing collagen synthesis and modulating inflammation.
post-laser erythema, collagen synthesis · standardised Centella extract
Pharmaceutics, 2024Madecassoside facilitated wound healing via antioxidative activity and collagen synthesis (pre-clinical).
wound healing · madecassoside
J Ethnopharmacol, 2008
Affiliation note. Publication links report the study authors and their affiliations. MIRU does not infer independence from an affiliation alone.
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Check an ingredient listCommon questions
What does Centella Callus Culture Extract do for skin?
It provides soothing support and helps calm visible redness while reinforcing the skin’s surface. The callus-culture process gives a stable source of Centella’s key compounds.
Is Centella Callus Culture Extract good for sensitive skin?
Yes, it’s commonly included in routines for easily‑upset skin because of its calming and barrier-supporting behaviour. The biotech production also reduces variability found in traditional plant extracts.
How is Centella Callus Culture Extract used in skincare?
You’ll usually find it in serums, essences, or creams designed for comfort and barrier support. It layers easily with most hydrating and soothing ingredients.
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