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Ingredient guide
acetyl hexapeptide-4
In short
Acetyl Hexapeptide‑4 is a stabilised form of Hexapeptide‑4 designed to stay active longer on the skin. It supports firmness and texture by engaging collagen‑related signalling pathways.
Reviewed against published evidence · editorially independent · no brand pays for placement
Works for
Firmness · Texture
Best used
Evening
What it is
N-terminally acetylated form of hexapeptide-4; acetylation at the amino terminus improves metabolic stability against aminopeptidase activity in the stratum corneum, extending the effective concentration reaching fibroblasts; targets the same procollagen I C-terminal receptor pathway as the parent peptide but with an improved half-life in formulation; hydrophilic and compatible with most aqueous systems.
Also found as
Related
Common questions
It helps improve the feel of elasticity and smoothness while maintaining better stability than its unmodified form.
It suits anyone interested in gentle peptide-based texture and elasticity support.
You’ll find it in water‑based serums or moisturisers that layer easily with most routines.
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Personal guidance only · For clinical concerns, see a dermatologist.