{
  "id": "zinc",
  "idVersion": 1,
  "ingredient": "Zinc",
  "route": "topical",
  "grade": "limited",
  "gradeLabel": "Limited",
  "claim": "Limited but consistent evidence in relation to calmer, clearer skin. More supportive than central.",
  "caveat": null,
  "published": "2026-09-19",
  "sources": [
    {
      "url": "https://doi.org/10.1111/dth.14252",
      "journal": "Dermatol Ther",
      "year": 2020,
      "n": null,
      "design": "Systematic review and meta-analysis",
      "duration": null,
      "percentages": [],
      "outcome": "inflammatory papule count, serum zinc",
      "finding": "Systematic review and meta-analysis: acne patients had significantly lower serum zinc; zinc reduced inflammatory papule counts as mono- or adjunct therapy.",
      "formulation": null
    },
    {
      "url": "https://pubmed.ncbi.nlm.nih.gov/23652948/",
      "journal": "J Drugs Dermatol",
      "year": 2013,
      "n": null,
      "design": null,
      "duration": null,
      "percentages": [],
      "outcome": "acne, sebum",
      "finding": "Zinc has antibacterial/anti-inflammatory and sebum-reducing effects; recommendation strength B (limited-quality evidence).",
      "formulation": null
    }
  ],
  "peopleReport": null
}