{
  "id": "retinoids",
  "idVersion": 1,
  "ingredient": "Retinoids (class)",
  "route": "topical",
  "grade": "strong",
  "gradeLabel": "Strong",
  "claim": "Topical retinoids as a class are among the most studied ingredients for skin texture over time.",
  "caveat": null,
  "published": "2026-09-19",
  "sources": [
    {
      "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472206/",
      "journal": "Cureus",
      "year": 2024,
      "n": null,
      "design": "Review",
      "duration": null,
      "percentages": [],
      "outcome": "acne",
      "finding": "The review names retinoids, antibiotics and benzoyl peroxide as the main treatment options for acne, and states that a retinoid with benzoyl peroxide is safe and effective without contributing to antibiotic resistance. (Its own trial data is eight adapalene/benzoyl-peroxide trials and is adapalene/BPO specific.)",
      "formulation": "adapalene with benzoyl peroxide"
    }
  ],
  "peopleReport": null
}