{
  "id": "niacinamide",
  "idVersion": 1,
  "ingredient": "Niacinamide",
  "route": "topical",
  "grade": "strong",
  "gradeLabel": "Strong",
  "claim": "Well studied in relation to a calmer, more even-looking complexion and a supported skin barrier.",
  "caveat": null,
  "published": "2026-09-19",
  "sources": [
    {
      "url": "https://pubmed.ncbi.nlm.nih.gov/16029679/",
      "journal": "Dermatologic Surgery",
      "year": 2005,
      "n": null,
      "design": "Double-blind split-face trial",
      "duration": "12 weeks",
      "percentages": [
        "5%"
      ],
      "outcome": "fine lines, hyperpigmented spots, red blotchiness, sallowness, elasticity",
      "finding": "Double-blind split-face, 5% niacinamide, 12 weeks: significant reductions in fine lines, hyperpigmented spots, red blotchiness and sallowness; improved elasticity.",
      "formulation": "5% niacinamide"
    },
    {
      "url": "https://pubmed.ncbi.nlm.nih.gov/18492135/",
      "journal": "Int J Cosmetic Science",
      "year": 2004,
      "n": null,
      "design": null,
      "duration": null,
      "percentages": [],
      "outcome": "yellowing, wrinkling, red blotchiness, hyperpigmented spots",
      "finding": "Confirmed reductions in yellowing, wrinkling, red blotchiness and hyperpigmented spots.",
      "formulation": null
    }
  ],
  "peopleReport": null
}